Establishment of an Acquired Lymphedema Model in the Mouse Hindlimb: Technical Refinement and Molecular Characteristics.
Identifieur interne : 000582 ( Main/Exploration ); précédent : 000581; suivant : 000583Establishment of an Acquired Lymphedema Model in the Mouse Hindlimb: Technical Refinement and Molecular Characteristics.
Auteurs : Daisuke Iwasaki ; Yuhei Yamamoto ; Naoki Murao ; Akihiko Oyama ; Emi Funayama ; Hiroshi FurukawaSource :
- Plastic and reconstructive surgery [ 1529-4242 ] ; 2017.
Descripteurs français
- KwdFr :
- ARN (analyse), ARN messager (analyse), Animaux, Facteur de croissance endothéliale vasculaire de type A (analyse), Facteur de croissance endothéliale vasculaire de type C (analyse), Immunohistochimie, Lymphe (physiologie), Lymphoedème (anatomopathologie), Lymphoedème (étiologie), Lymphographie, Membre pelvien, Modèles animaux de maladie humaine, Mâle, Noeuds lymphatiques (), Protéines suppresseurs de tumeurs (analyse), Protéines à homéodomaine (analyse), Réaction de polymérisation en chaine en temps réel, Récepteur-3 au facteur croissance endothéliale vasculaire (analyse), Souris, Souris de lignée C57BL, Système lymphatique (physiologie), Vert indocyanine.
- MESH :
- analyse : ARN, ARN messager, Facteur de croissance endothéliale vasculaire de type A, Facteur de croissance endothéliale vasculaire de type C, Protéines suppresseurs de tumeurs, Protéines à homéodomaine, Récepteur-3 au facteur croissance endothéliale vasculaire.
- anatomopathologie : Lymphoedème.
- physiologie : Lymphe, Système lymphatique.
- étiologie : Lymphoedème.
- Animaux, Immunohistochimie, Lymphographie, Membre pelvien, Modèles animaux de maladie humaine, Mâle, Noeuds lymphatiques, Réaction de polymérisation en chaine en temps réel, Souris, Souris de lignée C57BL, Vert indocyanine.
English descriptors
- KwdEn :
- Animals, Disease Models, Animal, Hindlimb, Homeodomain Proteins (analysis), Immunohistochemistry, Indocyanine Green, Lymph (physiology), Lymph Nodes (surgery), Lymphatic System (physiology), Lymphedema (etiology), Lymphedema (pathology), Lymphography, Male, Mice, Mice, Inbred C57BL, RNA (analysis), RNA, Messenger (analysis), Real-Time Polymerase Chain Reaction, Tumor Suppressor Proteins (analysis), Vascular Endothelial Growth Factor A (analysis), Vascular Endothelial Growth Factor C (analysis), Vascular Endothelial Growth Factor Receptor-3 (analysis).
- MESH :
- chemical , analysis : Homeodomain Proteins, RNA, RNA, Messenger, Tumor Suppressor Proteins, Vascular Endothelial Growth Factor A, Vascular Endothelial Growth Factor C, Vascular Endothelial Growth Factor Receptor-3.
- etiology : Lymphedema.
- pathology : Lymphedema.
- physiology : Lymph, Lymphatic System.
- surgery : Lymph Nodes.
- Animals, Disease Models, Animal, Hindlimb, Immunohistochemistry, Indocyanine Green, Lymphography, Male, Mice, Mice, Inbred C57BL, Real-Time Polymerase Chain Reaction.
Abstract
The pathophysiology of secondary lymphedema remains poorly understood. This study aimed to establish a consistent mouse hindlimb lymphedema model for further investigation of the mechanism and treatment of lymphedema.
DOI: 10.1097/PRS.0000000000002887
PubMed: 28027235
Affiliations:
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Le document en format XML
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<affiliation><nlm:affiliation>Sapporo, Hokkaido, Japan From the Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, University of Hokkaido.</nlm:affiliation>
<wicri:noCountry code="subField">University of Hokkaido</wicri:noCountry>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
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<term>Homeodomain Proteins (analysis)</term>
<term>Immunohistochemistry</term>
<term>Indocyanine Green</term>
<term>Lymph (physiology)</term>
<term>Lymph Nodes (surgery)</term>
<term>Lymphatic System (physiology)</term>
<term>Lymphedema (etiology)</term>
<term>Lymphedema (pathology)</term>
<term>Lymphography</term>
<term>Male</term>
<term>Mice</term>
<term>Mice, Inbred C57BL</term>
<term>RNA (analysis)</term>
<term>RNA, Messenger (analysis)</term>
<term>Real-Time Polymerase Chain Reaction</term>
<term>Tumor Suppressor Proteins (analysis)</term>
<term>Vascular Endothelial Growth Factor A (analysis)</term>
<term>Vascular Endothelial Growth Factor C (analysis)</term>
<term>Vascular Endothelial Growth Factor Receptor-3 (analysis)</term>
</keywords>
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<term>ARN messager (analyse)</term>
<term>Animaux</term>
<term>Facteur de croissance endothéliale vasculaire de type A (analyse)</term>
<term>Facteur de croissance endothéliale vasculaire de type C (analyse)</term>
<term>Immunohistochimie</term>
<term>Lymphe (physiologie)</term>
<term>Lymphoedème (anatomopathologie)</term>
<term>Lymphoedème (étiologie)</term>
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<term>Membre pelvien</term>
<term>Modèles animaux de maladie humaine</term>
<term>Mâle</term>
<term>Noeuds lymphatiques ()</term>
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<term>Protéines à homéodomaine (analyse)</term>
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<term>Souris de lignée C57BL</term>
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<term>Vert indocyanine</term>
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<term>RNA, Messenger</term>
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<term>Vascular Endothelial Growth Factor A</term>
<term>Vascular Endothelial Growth Factor C</term>
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<term>ARN messager</term>
<term>Facteur de croissance endothéliale vasculaire de type A</term>
<term>Facteur de croissance endothéliale vasculaire de type C</term>
<term>Protéines suppresseurs de tumeurs</term>
<term>Protéines à homéodomaine</term>
<term>Récepteur-3 au facteur croissance endothéliale vasculaire</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lymphedema</term>
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<term>Système lymphatique</term>
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<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Lymph</term>
<term>Lymphatic System</term>
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<term>Disease Models, Animal</term>
<term>Hindlimb</term>
<term>Immunohistochemistry</term>
<term>Indocyanine Green</term>
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<term>Real-Time Polymerase Chain Reaction</term>
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<term>Lymphographie</term>
<term>Membre pelvien</term>
<term>Modèles animaux de maladie humaine</term>
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<term>Noeuds lymphatiques</term>
<term>Réaction de polymérisation en chaine en temps réel</term>
<term>Souris</term>
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<front><div type="abstract" xml:lang="en">The pathophysiology of secondary lymphedema remains poorly understood. This study aimed to establish a consistent mouse hindlimb lymphedema model for further investigation of the mechanism and treatment of lymphedema.</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Funayama, Emi" sort="Funayama, Emi" uniqKey="Funayama E" first="Emi" last="Funayama">Emi Funayama</name>
<name sortKey="Furukawa, Hiroshi" sort="Furukawa, Hiroshi" uniqKey="Furukawa H" first="Hiroshi" last="Furukawa">Hiroshi Furukawa</name>
<name sortKey="Iwasaki, Daisuke" sort="Iwasaki, Daisuke" uniqKey="Iwasaki D" first="Daisuke" last="Iwasaki">Daisuke Iwasaki</name>
<name sortKey="Murao, Naoki" sort="Murao, Naoki" uniqKey="Murao N" first="Naoki" last="Murao">Naoki Murao</name>
<name sortKey="Oyama, Akihiko" sort="Oyama, Akihiko" uniqKey="Oyama A" first="Akihiko" last="Oyama">Akihiko Oyama</name>
<name sortKey="Yamamoto, Yuhei" sort="Yamamoto, Yuhei" uniqKey="Yamamoto Y" first="Yuhei" last="Yamamoto">Yuhei Yamamoto</name>
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